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Pharmacology EBooks

Free Pharmacology EBooks for Download

Below we have listed all the Free Pharmacology EBooks for download. Feel free to comment on any Pharmacology EBooks for download or answer by the comment feature available on the page.
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Mass Spectrometry in Drug Metabolism and Pharmacokinetics Book: Within the pharmaceutical industry, the mass spectrometer was long considered a useful and challenging analytical tool largely limited to the specialist user. The steady movement from specialist use to general use gained considerable speed in the 1990s, particularly due to the development of practical, sensitive liquid chromatography–mass spectrometry (LC–MS) interfaces and advances in the microelectronics. The rapid proliferation of quadrupole ion trap, linear ion trap, orbitrap, quadrupole mass filter, time-of-flight, and other types of mass spectrometers has impacted the industry from the earliest stages of disease determination through the final stages of clinical testing. This book, based on an American Society for Mass Spectrometry (ASMS) session, which I was fortunate enough to chair, will examine several of the ways in which mass spectrometry continues to have a profound influence on the direction and speed of drug discovery and development, especially in the area of drug metabolism (DM) and pharmacokinetics (PK).

Date Added: 10/29/2010 2:16:56 AM | Visits: 23968


Pharmacology and Vitreoretinal Surgery Developments in Ophthalmology: Book author: Arnd Gandorfer

Date Added: 10/28/2010 11:52:55 PM | Visits: 23038


Clinical Ocular Toxicology Drug Induced Ocular Side Effects: Book author: Frederick T. Fraunfelder

Date Added: 10/28/2010 11:26:50 PM | Visits: 24041


Mass Spectrometry in Drug Metabolism and Pharmacokinetics Book: The first step in discovering a new medicine is to identify a therapeutic target. Drugs in today’s market as well as those in recent clinical testing target less than 500 biomolecules, with more than 10 times that many potential therapeutic targets waiting to be discovered and developed (Drews, 2000). More than 50% of the newly approved drugs result from R&D involving previously clinically tested and validated targets. Once a target has been validated (proven to be related to the disease process), high-throughput screening methods may be used to determine initial structural leads. Compounds are assessed for target affinity and for their “druglike” properties, including absorption, distribution, metabolism, and excretion (ADME) using a series of in vivo and in vitro tests. The results of these tests are used to improve the structure and therefore the properties of the next round of test compounds, until ultimately one or more acceptable compounds are advanced forward in the process. This stage of discovery, which can be lengthy and difficult to predict, is generally referred to as lead optimization.

Date Added: 10/28/2010 11:22:31 PM | Visits: 23935


The Renal Drug Handbook Book: Book author: Aileen Currie and Caroline Ashley

Date Added: 10/28/2010 11:21:50 PM | Visits: 24214


Psychiatric Drug Reactions and Interactions: Book author: Jerome Z. Litt

Date Added: 10/28/2010 11:21:47 PM | Visits: 24413


CDC recommended infection control practices for dentistry: CDC recommended infection control practices for dentistry

Date Added: 10/25/2010 1:44:53 AM | Visits: 23975


PMFARMA Digital [Espaol]: PMFARMA Digital [Espaol]

Date Added: 10/25/2010 1:44:23 AM | Visits: 23183


Pharmacy On Line [English]: Pharmacy On Line [English]

Date Added: 10/25/2010 1:43:49 AM | Visits: 23255


Pharmacologie Universit de Rennes [Franais]: Pharmacologie Universit de Rennes [Franais]

Date Added: 10/25/2010 1:43:09 AM | Visits: 24443


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